In-silico Drug Designing Methods

Objective: To introduce new in-silico drug designing methods.

Methods: In-silico drug designing is the identification of the drug target molecule by employing bioinformatics tools.
Ligand based drug designing and Structure based drug designing are the two different types of in-silico drug
designing, absorption, distribution, metabolism and excretion properties based drug delivery system models
visualized by scientist yields real time monitoring and control over the duration of drug discovery process. It acts as an
in silico tool for investigating the therapies of the different types of rare diseases. The basic steps in in-silico drug
designing are (a) disease related genomics (b) target identification and validation (c) lead optimization (d) preclinical
trials (e) clinical trials. In this the selection of a disease determines the biochemical basis of the disease process. The
present compilation provides an overview of the various in-silico drug designing models for the drug delivery system.

Result: In-silico technology alone cannot guarantee the identification of new, safe and effective lead compound but
more realistically future success depends on the proper integration of new promising technologies with the
experience and strategies of classical medicinal chemistry.

Conclusion: Safe and effective, in-silico drug designing methods are crucial for investigating and producing the new,
specific therapies for the treatment of a wide range of rare diseases.